string = "\"@Jeff_Atwood Thank you for #stackoverflow', 'All hail @Joel_Spolsky t.co/Gsb7V1oVLU #stackoverflow\":!#"
for punc in '":!#':
string = string.replace(punc, '')
print(string)
c3RyaW5nID0gIlwiQEplZmZfQXR3b29kIFRoYW5rIHlvdSBmb3IgI3N0YWNrb3ZlcmZsb3cnLCAnQWxsIGhhaWwgQEpvZWxfU3BvbHNreSB0LmNvL0dzYjdWMW9WTFUgI3N0YWNrb3ZlcmZsb3dcIjohIyIKZm9yIHB1bmMgaW4gJyI6ISMnOgoJc3RyaW5nID0gc3RyaW5nLnJlcGxhY2UocHVuYywgJycpCnByaW50KHN0cmluZyk=