import re
s = "Employee ID DF856, Year 2016, Department Finance, Team 2, Location 112 20161 12016 120162"
print(re.findall(r'(?<!\d)(?!2016(?!\d))\d{3,}', s))
print([x for x in re.findall(r'\d{3,}', s) if x != "2016"])
aW1wb3J0IHJlCnMgPSAiRW1wbG95ZWUgSUQgREY4NTYsIFllYXIgMjAxNiwgRGVwYXJ0bWVudCBGaW5hbmNlLCBUZWFtIDIsIExvY2F0aW9uIDExMiAyMDE2MSAxMjAxNiAxMjAxNjIiCnByaW50KHJlLmZpbmRhbGwocicoPzwhXGQpKD8hMjAxNig/IVxkKSlcZHszLH0nLCBzKSkKCnByaW50KFt4IGZvciB4IGluIHJlLmZpbmRhbGwocidcZHszLH0nLCBzKSBpZiB4ICE9ICIyMDE2Il0pCg==