import re
l = ['palsar_cprof_1_1_10_0.sdat #1','palsar_0.99_10_1_0.sdat #2','srtm_cprof_10_10_5_0.sdat #3','srtm_10_10_5_0.sdat #4']
rx = re.compile(r'^[^_]*_\d')
l = list(filter(rx.search, l))
print(l)