import re
text = "1. 1xyz-2xyz - it's OK\n2. 1-2xyz - it's OK\n3. 1xyz - it's OK\n4. 1-2 - there should be no match"
pattern = r"\b([0-9])(xyz)?(?:-([0-9])(xyz)?)?\b(?(2)|(?(4)|(?!)))"
print( [x.group() for x in re.finditer(pattern, text)] )