<?php
$patterns = ["re", "get", "ER"];
$string = "You are definitely getting\nbetter\ntoday";
$alternations = implode('|', $patterns);
$re = '\R?(?!(?<=\s)(?:'.$alternations.')(?=\s))\S*(?:'.$alternations.')\S*';
$string = preg_replace('#'.$re.'#i', '', $string);
$string = preg_replace('#\h{2,}#', ' ', $string);
echo $string;