import re

s1 = """
   Python is a high-level, interpreted,  Good&
   general|purpose| programming| language. 
   Its design philosophy emphasizes code   Better
   readability with the use of significant Best
   indentation| 
   """
pattern = r'^[^|\n]*(?<!\S)(?:Good|Better|Best)(?!\S)[^\n|]*$'

print(re.findall(pattern, s1, re.M))