library(stringr)
s <- "-+?="
str_replace_all(s, "([\\p{P}\\p{S}])(?=[\\p{P}\\p{S}])", "\\1 ")
str_replace_all(s, "(?<=[\\p{P}\\p{S}])(?=[\\p{P}\\p{S}])", " ")
gsub("(?<=[[:punct:]])(?=[[:punct:]])", " ", s, perl=TRUE)