<?php

$obj = json_decode('{
 "Autenticacao": {
    "login": 100000000000,
    "senha": "123"
 },
 "operacao": {
    "nome": false,
    "endereco": "rua sei la",
    "numero": "123"
 }
}');

foreach ($obj as &$main) {
    foreach ($main as &$value) {
        $value = filter_var($value, FILTER_SANITIZE_SPECIAL_CHARS);
    }
}

var_dump($obj);