using System;
using System.Linq;
using System.Collections.Generic;
using System.Globalization;

public class Test
{
    
	public static void Main()
	{
            string txtUnwantedText = "-,$,!,@,#,$,%,^,&,*,(,),.com,.net,.org";
            string textBox1Lines = @"555-555-1212
I want's a lemon's.
google.com
1&1 Hosting";

            string[] replaceStrings = txtUnwantedText.Split(',');
            List<string> lines = new List<string>(textBox1Lines.Split(new[]{Environment.NewLine},StringSplitOptions.None));
            for (int i = 0; i < lines.Count; i++)
                foreach (string repl in replaceStrings)
                    lines[i] = lines[i].Replace(repl, "");
                    
            foreach(string line in lines)            
                Console.WriteLine(line);

	}
}