#!/usr/bin/env python
 
import base64
import sys
import string
 
my_base64chars  = "+AbCdEfGhIjKlMnOpQrStUvWxYz0123456789ZyXwVuTsRqPoNmLkJiHgFeDcBa/"
std_base64chars = "ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/"
s = "SfU72WQ9YvMZ2GQZYWAmYWUiYvUkxvZkYfUk1yBJ2yUm0fUR0HQ9YWA61HMZxXI62yB8YvNJzvMVYWMknSlLzixo18MilHh"
s = s.translate(string.maketrans(my_base64chars, std_base64chars))
data = base64.b64decode(s)
 
print data

Standard output is empty

Traceback (most recent call last):
  File "prog.py", line 11, in <module>
  File "/usr/lib/python2.7/base64.py", line 78, in b64decode
    raise TypeError(msg)
TypeError: Incorrect padding