fork download
  1. import re
  2. text = """
  3. Date: ClinicalTrials.gov processed this data on October 25, 2016
  4.  
  5. URL: https://c...content-available-to-author-only...s.gov/show/NCT00000113
  6.  
  7. Org Study Id: NEI-9
  8.  
  9. NCT ID: NCT00000113
  10.  
  11. Title: Correction of Myopia Evaluation Trial (COMET)
  12.  
  13. Official Title: Correction of Myopia Evaluation Trial (COMET)
  14.  
  15. Summary:
  16. To evaluate whether progressive addition lenses (PALs) slow the rate of progression of
  17. juvenile-onset myopia (nearsightedness) when compared with single vision lenses, as measured
  18. by cycloplegic autorefraction. An additional outcome measure is axial length, as measured by
  19. A-scan ultrasonography.
  20.  
  21. To describe the natural history of juvenile-onset myopia in a group of children receiving
  22. conventional treatment (single vision lenses).
  23.  
  24.  
  25. Description:
  26. Myopia (nearsightedness) is an important public health problem, which entails substantial
  27. societal and personal costs. It is highly prevalent in our society and even more frequent in
  28. Asian countries; furthermore, its prevalence may be increasing over time. High myopia
  29. contributes to significant loss of vision and blindness. At present, the mechanisms involved
  30. in the etiology of myopia are unclear, and there is no way to prevent the condition. Current
  31. methods of correction require lifelong use of lenses or surgical treatment, which is
  32. expensive and may lead to complications. The rationale for this trial, the Correction of
  33. Myopia Evaluation Trial (COMET), arises from the convergence of research involving (1) the
  34. link between accommodation and myopia in children and (2) animal models of myopia showing
  35. the important role of the visual environment in eye growth. A contribution of this research
  36. is that blur is a critical component in the development of myopia. The primary aim of COMET,
  37. to evaluate the efficacy of progressive addition lenses, a noninvasive intervention, in
  38. slowing the progression of myopia, follows from this line of reasoning. These lenses should
  39. provide clear visual input over a range of viewing distances without focusing effort by the
  40. child. The comparison of myopia progression in children treated with PALs versus single
  41. vision lenses will allow the quantification of the effect of PALs on myopia progression
  42. during the followup period.
  43.  
  44. The COMET is a multicenter, randomized, double-masked clinical trial to evaluate whether
  45. PALs slow the progression of juvenile-onset myopia as compared with single vision lenses.
  46. The study is a collaborative effort that involves a Study Chair at the New England College
  47. of Optometry; four clinical centers at colleges of optometry in Boston, Birmingham,
  48. Philadelphia, and Houston; and a Coordinating Center at the State University of New York at
  49. Stony Brook.
  50.  
  51. The sample size goal, 450 children with myopia in both eyes who met specific inclusion and
  52. exclusion criteria, was attained with the enrollment of 469 children in one year. Children
  53. were identified from school screenings, clinic records, and referrals from local
  54. practitioners. Eligible children were randomly assigned to receive progressive addition or
  55. single vision lenses. Participating children are being examined at 6-month intervals
  56. following baseline, for at least 3 years, to measure changes in refractive error and to
  57. update prescriptions, according to a specified protocol. A dilated examination to evaluate
  58. the study outcome measures is performed at the annual study visits. A standardized, common
  59. protocol is used at all centers.
  60.  
  61. The primary outcome of the study is progression of myopia, defined as the magnitude of the
  62. change relative to baseline in spherical equivalent refraction, determined by cycloplegic
  63. autorefraction. The secondary outcome of the study is axial length measured by A-scan
  64. ultrasonography.
  65.  
  66.  
  67. Overall Status: Completed
  68.  
  69. Start Date: September 1997
  70.  
  71. Phase: Phase 3
  72.  
  73. Gender: Both
  74.  
  75. Minimum Age: 6
  76.  
  77. Maximum Age: 12
  78.  
  79. Healthy Volunteers: No
  80.  
  81. Keywords: ['myopia','nearsightedness']
  82. """
  83.  
  84. print(re.split(r"\n{2,}(?=\S)", text))
Success #stdin #stdout 0.01s 23352KB
stdin
Standard input is empty
stdout
['\nDate: ClinicalTrials.gov processed this data on October 25, 2016', 'URL: https://c...content-available-to-author-only...s.gov/show/NCT00000113', 'Org Study Id: NEI-9', 'NCT ID: NCT00000113', 'Title: Correction of Myopia Evaluation Trial (COMET)', 'Official Title: Correction of Myopia Evaluation Trial (COMET)', 'Summary: \n      To evaluate whether progressive addition lenses (PALs) slow the rate of progression of\n      juvenile-onset myopia (nearsightedness) when compared with single vision lenses, as measured\n      by cycloplegic autorefraction. An additional outcome measure is axial length, as measured by\n      A-scan ultrasonography.\n\n      To describe the natural history of juvenile-onset myopia in a group of children receiving\n      conventional treatment (single vision lenses).\n    ', 'Description: \n      Myopia (nearsightedness) is an important public health problem, which entails substantial\n      societal and personal costs. It is highly prevalent in our society and even more frequent in\n      Asian countries; furthermore, its prevalence may be increasing over time. High myopia\n      contributes to significant loss of vision and blindness. At present, the mechanisms involved\n      in the etiology of myopia are unclear, and there is no way to prevent the condition. Current\n      methods of correction require lifelong use of lenses or surgical treatment, which is\n      expensive and may lead to complications. The rationale for this trial, the Correction of\n      Myopia Evaluation Trial (COMET), arises from the convergence of research involving (1) the\n      link between accommodation and myopia in children and (2) animal models of myopia showing\n      the important role of the visual environment in eye growth. A contribution of this research\n      is that blur is a critical component in the development of myopia. The primary aim of COMET,\n      to evaluate the efficacy of progressive addition lenses, a noninvasive intervention, in\n      slowing the progression of myopia, follows from this line of reasoning. These lenses should\n      provide clear visual input over a range of viewing distances without focusing effort by the\n      child. The comparison of myopia progression in children treated with PALs versus single\n      vision lenses will allow the quantification of the effect of PALs on myopia progression\n      during the followup period.\n\n      The COMET is a multicenter, randomized, double-masked clinical trial to evaluate whether\n      PALs slow the progression of juvenile-onset myopia as compared with single vision lenses.\n      The study is a collaborative effort that involves a Study Chair at the New England College\n      of Optometry; four clinical centers at colleges of optometry in Boston, Birmingham,\n      Philadelphia, and Houston; and a Coordinating Center at the State University of New York at\n      Stony Brook.\n\n      The sample size goal, 450 children with myopia in both eyes who met specific inclusion and\n      exclusion criteria, was attained with the enrollment of 469 children in one year. Children\n      were identified from school screenings, clinic records, and referrals from local\n      practitioners. Eligible children were randomly assigned to receive progressive addition or\n      single vision lenses. Participating children are being examined at 6-month intervals\n      following baseline, for at least 3 years, to measure changes in refractive error and to\n      update prescriptions, according to a specified protocol. A dilated examination to evaluate\n      the study outcome measures is performed at the annual study visits. A standardized, common\n      protocol is used at all centers.\n\n      The primary outcome of the study is progression of myopia, defined as the magnitude of the\n      change relative to baseline in spherical equivalent refraction, determined by cycloplegic\n      autorefraction. The secondary outcome of the study is axial length measured by A-scan\n      ultrasonography.\n    ', 'Overall Status: Completed', 'Start Date: September 1997', 'Phase: Phase 3', 'Gender: Both', 'Minimum Age: 6', 'Maximum Age: 12', 'Healthy Volunteers: No', "Keywords: ['myopia','nearsightedness']\n"]